Extraction chamber for the purification of Islets of Langerhans from whole pancreatic tissue, and an array of infusion cells designed to assess biochemical activity of isolated islet cells in vitro, prior to cryopreservation and reflux implantation. These have been used in clinical trials to reverse insulin-dependent diabetes. This project also led to the development of temperature controlled microscope stages of various designs (liquid recirculation, Peltier, and liquid nitrogen/Joule heat balance) for the precise control of biological specimen temperature from -100° C to +60° C.
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